Artificial intelligence could reshape research and care in disorders of consciousness

The diagnosis and management of disorders of consciousness (DoC) currently relies on complex multimodal assessments by experienced multidisciplinary teams, which are often unavailable in non-specialist care settings. Artificial-intelligence-based approaches could aid DoC prognostication and care in such settings, as well as yielding new mechanistic and therapeutic insights into DoC.

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IRCCS, Fondazione Don Carlo Gnocchi ETS, Florence, Italy

Institute of Health Informatics, University College London, London, UK

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Correspondence to Anna Estraneo.

The authors declare no competing interests.

Estraneo, A., Molteni, E. Artificial intelligence could reshape research and care in disorders of consciousness. Nat Rev Neurol (2026). https://doi.org/10.1038/s41582-026-01229-4

Version of record: 27 June 2026

DOI: https://doi.org/10.1038/s41582-026-01229-4