Berkeley Lab to Lead 13 New Genesis Mission AI Projects

Today, the U.S. Department of Energy announced funding for new projects that will harness artificial intelligence to accelerate discovery. Lawrence Berkeley National Laboratory (Berkeley Lab) will lead 13 projects and collaborate as a partner on more than 30 others.

The projects are part of DOE’s Genesis Mission, a historic national initiative that aims to build the world’s most powerful integrated science discovery platform. By uniting government, industry, academia, and philanthropy, it seeks to accelerate breakthroughs in energy, scientific discovery, and national security through a new platform that combines AI, supercomputing, quantum systems, and advanced scientific instruments.

Berkeley Lab’s contributions to the Genesis Mission build on decades of research in high-performance computing, managing large datasets, and pioneering AI models. Researchers will lead new projects across multiple disciplines, advancing fields including critical minerals, materials, manufacturing, fusion, and energy.

“By developing advanced AI tools and combining them with high-quality datasets and high-performance computing, our researchers are maximizing their scientific impact and speeding up discovery,” said Kathy Yelick, director of Berkeley Lab. “Beyond that, the Genesis Mission is also an opportunity to pioneer better AI tools and approaches for all of science, which will bring payoffs for generations to come.”

The goal of the Phase 1 Genesis Mission projects is to identify promising pathways toward transformative scientific capabilities and establish a foundation for future investment and scale. Project teams will design and demonstrate research workflows that integrate AI with scientific investigation, while rigorously evaluating whether those approaches can accelerate discovery, improve predictive capabilities, enhance experimentation, or generate new scientific insights.

The projects that Berkeley Lab leads are:

Lawrence Berkeley National Laboratory (Berkeley Lab) is committed to groundbreaking research focused on discovery science and solutions for abundant and reliable energy supplies. The lab’s expertise spans materials, chemistry, physics, biology, earth and environmental science, mathematics, and computing. Researchers from around the world rely on the lab’s world-class scientific facilities for their own pioneering research. Founded in 1931 on the belief that the biggest problems are best addressed by teams, Berkeley Lab and its scientists have been recognized with 17 Nobel Prizes. Berkeley Lab is a multiprogram national laboratory managed by the University of California for the U.S. Department of Energy’s Office of Science.

DOE’s Office of Science is the single largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit energy.gov/science.